Triethanolamine cancer. The studies suggest there is inadequate evidence for carcinogenicity in humans. You’ll see these listed on the ingredient label as “MEA, DEA, & TEA,” abbreviations for monoethanolamine, diethanolamine, and triethanolamine. The most serious concern about these ingredients is that they may increase risk for cancer, especially with repeated and prolonged use. Oxford Academic Loading May 19, 2025 · The National Cancer Institute nominated triethanolamine for study because of its widespread use in cosmetics and other consumer products, its high potential for worker exposure due to its many industrial uses, and its potential for conversion to the carcinogen N-nitrosodiethanolamine. . Triethanolamine has been evaluated by the International Agency for Research on Cancer (IARC) as carcinogenicity group 3, not classifiable as to its carcinogenic potential in humans. , 1992). Triethanolamine (TEA), a widely used nongenotoxic alcoholamine, has recently been reported to cause an increased incidence of liver tumors in female B6C3F1 mice, but not in males nor in Fischer 344 rats. The National Cancer Institute nominated triethanolamine for study because of its widespread use in cosmetics and other consumer products, its high potential for worker exposure due to its many industrial uses, and its potential for conversion to the carcinogen N-nitrosodiethanolamine. Positivity: For each chemical with a positive (carcinogenic) experiment in the Carcinogenic Potency Database (CPDB), results are included on carcinogenic potency (TD50) in each species and target sites in males and females. The National Cancer Institute nominated triethanolamine for study because of its wide- spread use in cosmetics and other consumer products, its high potential for worker exposure due to its many industrial uses, and its potential for conversion to the carcinogen N-nitrosodiethanolamine. Nitrosamines are impurities that can show up in a wide array of cosmetics ingredients—including diethanolamine (DEA) and triethanolamine (TEA)—and products. The analysis determined that triethanolamine is not classifiable as cancer-causing. Think all those suds Sep 10, 2024 · Our comprehensive guide to cosmetic ingredients to avoid helps you find and purchase safe, healthy products for you and your family. Choline deficiency induces liver cancer in rodents, May 19, 2025 · The National Cancer Institute nominated triethanolamine for study because of its widespread use in cosmetics and other consumer products, its high potential for worker exposure due to its many industrial uses, and its potential for conversion to the carcinogen N-nitrosodiethanolamine. Occupational exposure may occur by inhalation and dermal contact, particularly in metal-machining occupations. Positivity is determined by an author’s opinion in a published paper. Jan 1, 1992 · The chronic toxicity and carcinogenic potential of triethanolamine was examined in B6C3F1 mice. TEA is a chemical intermediate in the manufacture of anionic and nonionic surfactants. No The National Cancer Institute nominated triethanolamine for study because of its wide- spread use in cosmetics and other consumer products, its high potential for worker exposure due to its many industrial uses, and its potential for conversion to the carcinogen N-nitrosodiethanolamine. Triethanolamine is a viscous liquid widely used as a corrosion inhibitor, a surface-active agent and an intermediate in various products including metalworking fluids, oils, fuels, paints, inks, cement, cosmetic and personal products, as well as herbicide and algicide formulations. TEA had no carcinogenic or cocarcinogenic activity when dermally applied to mice for 18 months. Jul 10, 2018 · While federal regulations allow small doses of Triethanolamine in beauty and personal care items, they have proved hazardous short term and long term effects ranging from skin and eye irritation, to damaging the respiratory and immune systems and inciting cancer. Aug 9, 2021 · Ethanolamines are ammonia compounds used in cosmetics as emulsifiers or foaming agents. , 1986; Konishi et al. The National Cancer Institute nominated triethanolamine for study because of its widespread use in cosmetics and other consumer products, its high potential for worker exposure due to its many industrial uses, and its potential for conversion to the carcinogen N -nitrosodiethanolamine. There was very little skin sensitization. Triethanolamine, disolved in distilled water at levels… The formation of N -nitrosodiethanolamine in amounts that would cause liver cancer in vivo appears, however, unlikely since no treatment-related liver cancers have been observed in oral or dermal triethanolamine carcinogenicity studies in mice or rats (Hoshino & Tanooka, 1978; Maekawa et al. Triethanolamine (TEA) is used in a number of industrial processes, and in the manufacture of a wide variety of consumer products. Clinical skin testing of TEA and cosmetic products containing TEA and DEA showed mild skin irritation in concentrations above 5%. mwnjxti sbmu ojqz uezh vryi rnam igtzs yjmn dwymxt mjlbv